844 research outputs found

    Killing Symmetry in Special Axially Symmetric Static Spacetimes in Teleparalel Theory of Gravitation

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    In this paper we are searching for teleparallel Killing vector fields of special axially symmetric static spacetimes in teleparallel theory of gravitation by using direct integration and algebraic techniques. After thorough investigations, the whole problem is divided into three cases under different constraints. Two of the said cases give contradiction, while one of them gives the solution of the system comprising the killing equations in the form of killing vector fields. The dimension of the killing symmetry in this case is 10

    A respectful design framework: incorporating indigenous knowledge in the design process

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    To stay within the planetary boundaries, we have to take responsibility, and this includes designers. This requires new perspectives on design. In this work, we focus on a co-design project with indigenous communities. Within such communities, indigenous knowledge is central. Indigenous knowledge acknowledges that the world is alive and that we, as humans, are merely a small part. Central in our approach is Sheehan’s respectful design, which ensures a central place for indigenous knowledge in the design process. However, Sheehan’s approach does not state in pragmatic terms how such a design approach can be achieved. Some of the co-design processes we engaged in led to respectful design spaces, others did not. This helped us to identify patterns of dynamics that are essential for respectful design. At the core of our findings lies the observation that in order to reach a respectful design space, in which indigenous knowledge is embedded, a shared dialogical space between community and designer is essential

    Mitigating Ethno-Cultural Differences Ethical Guidelines for ICT Development in an Indigenous Community

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    Community engagement is necessary for the success and sustainability of Information and Communication Technologies for Development (ICT4D) projects. To ensure active participation of community, researchers need to understand and adhere to the local cultural norms and adapt in the lifestyle of people. These cultural norms are mainly unwritten and implicit in nature. Hence the researchers spend maximum time of their field visits in observing and developing understanding of the community's life. In our long-term partnership with the indigenous Penan community of Long Lamai in Malaysian Borneo, we co-developed written guidelines for researchers and visitors. The researchers demonstrated their interest in aligning research process to the community's cultural values, however norm internalisation and development of associated behaviour is still a challenging. The written guidelines are yet only one of the attempts to the practices of community researchers' engagement and we are refining our methodology to enhance the researchers' learning process

    A comprehensive review of the classification of fibromyalgia, its possible genetic and environmental causes, and its epidemiology in Pakistan

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    Fibromyalgia (FM) is a common form of chronic pain that causes pain all over the body. It is thought to affect between 1% and 5% of the world's people. It happens more often in adults, but it can also happen in children. Its exact cause and effect are still not known. However, it is thought to be linked to neuronal over-sensitization, decreased conditioned pain modulation (CPM), cognitive dysfunction, dementia, and problems with how the brain processes information. It is now a disorder with physical symptoms (SSD). FM does not run in families. But it seems to happen more often in families where FM has happened before. One of the most common reasons why people get fibromyalgia is an SNP in the serotonin transporter gene, which can also cause emotional stress. The effects of genetic polymorphisms on serotonergic and catecholaminergic processes in the central nervous system seem to make fibromyalgia more likely. It can be stopped if it is found and treated quickly. Physical therapy and other treatments that don't involve drugs should be made to fit the person with FM. The Food and Drug Administration (FDA) has given the go-ahead for three treatments. In this review article, we looked again at the possible causes, effects, and treatments for fibromyalgia syndrome. &nbsp

    Value of routine preoperative tests for coagulation before elective cranial surgery. Results of an institutional audit and a nationwide survey of neurosurgical centers in Pakistan

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    Background: Routine preoperative blood testing has become a dogma. The general practice is to order preoperative workup as a knee-jerk response rather than individualize it for each patient. The fact that the bleeding brain tends to swell, which coupled with limited options for proximal control, packing, and overall hemostasis, leads to an overemphasis on the preoperative coagulation profile.Material and methods: This is a retrospective review of the medical records of patients admitted at Aga Khan University Hospital from January 2010 to December 2015 for an elective craniotomy. The hospital registry was used to identify files for review. Data were collected on a predefined proforma. A nationwide survey was performed, and 30 neurosurgery centers were contacted across Pakistan to confirm the practice of preoperative workup.Results: The survey revealed that all centers had a similar practice of preoperative workup. This included complete blood count, serum electrolytes, and coagulation profile, including prothrombin time, activated partial thromboplastin time (aPTT), and international normalized ratio (INR). A total of 1800 files were reviewed. Nine (0.5%) patients were found to have deranged clotting profile without any predictive history of clotting derangement; 56% were male and 44% were female. Median age was 32 years with an interquartile range of 27 years. Median aPTT was (40.8 with 20.8 IQR). Median INR was (1.59 with 0.48 IQR). Median blood loss was (400 with 50 IQR). No significant association between coagulation profile (aPTT, INR) and blood loss was found (P = 0.85, r = -0.07).Conclusions: We conclude that patients without a history of coagulopathy and normal physical examination do not require routine coagulation screening before elective craniotomy
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